One of the neurodevelopmental illnesses is Autism Spectrum Disorder (ASD). Regression autism affects about one-fifth of children with ASD. The Adenosine Monophosphate (AMP)-Activated Protein Kinase (AMPK) regulates the balance of ATP metabolism in mitochondria, which is dysfunctional in regressive autism. This sensor kinase has been found to help in axonal development in studies. Exercise has been indicated as one of the most powerful variables in increasing mitochondrial activity and AMPK levels. Physical activity has been shown to boost social abilities. Physical exercise programs, when properly structured, may create an enjoyable and safe environment for children to engage with one another. Above all, we expected that physical activities may improve mitochondrial activity and lessen autistic children’s symptoms.
